Saturday Special โ The Mushroom Issue
๐ Mushroom Deep Research โ Saturday Special
March 14, 2026
๐ Mushroom Computers: Memristors from Shiitake
Researchers at Ohio State University built memristors โ key components of neuromorphic computers โ from shiitake mycelium. The fungal mycelium acts as a memory switch capable of processing high-frequency signals, and it’s biodegradable. This isn’t a metaphor: it’s literally living computation powered by mushrooms. Silicon is sweating.
ScienceDaily โ Living computers powered by mushrooms
๐ Psilocybin Antidepressant โ Without the Hallucinations
Fresh off the press: scientists synthesized a modified form of psilocin (the active compound in magic mushrooms) that preserves the therapeutic effect on serotonin receptors but eliminates hallucinations. Preclinical tests in mice โ it works. This could be a game-changer: depression therapy without a 6-hour supervised trip. Published in the Journal of Medicinal Chemistry this week.
Neuroscience News โ Healing Without Hallucinations
๐ Mushrooms Invented Psilocybin Twice โ Independently
Convergent evolution at full throttle: magic mushrooms and fiber caps (completely unrelated species) developed different biochemical pathways to synthesize the exact same compound โ psilocybin. Why? Scientists don’t know. Maybe predator defense. Maybe the universe just wants us to trip. NYT wrote a whole piece about it.
NYT โ How Psychedelic Mushrooms Evolved Their Magic
๐ Mushrooms Paint Self-Portraits and Recite Poetry
The Bionic in the Wires project hooks electrodes to mushrooms, reads their bioelectric signals, and translates them into bionic arm movements. The result: mushrooms literally paint with brushes and generate spoken-word poetry. BBC Science Focus listed it among the strangest science stories of 2025. NPR did a segment on mushroom concerts. We live in the future, and it’s weird.
Boing Boing โ Mushroom with bionic arms paints ยท NPR โ Mushroom bioelectricity into music
๐ Living Building Material from Mycelium + Bacteria
Engineers developed a self-healing construction material by combining fungal mycelium with bacterial cells. The material is alive โ it can grow and repair cracks. This isn’t just a styrofoam replacement: it’s a potential revolution in construction. Self-healing concrete made from mushrooms sounds like sci-fi, but it’s already published in a peer-reviewed journal.
ScienceDaily โ Living material from fungi
๐ Lion’s Mane: From Hype to Science โ Epilepsy and Neuroprotection
Lion’s Mane has long been the darling of biohackers, but science is finally catching up. New 2025 studies explore its potential for epilepsy (alongside reishi) and neuroprotective effects during chemotherapy. NGF (nerve growth factor) โ “fertilizer for neurons” โ is stimulated by compounds in Lion’s Mane. Most data is still from mice and in vitro, but the direction is hot.
Realm of Caring โ Reishi and Lion’s Mane for Epilepsy
๐ The Mushroom Matrix: Fungal Biochar for Everything
A fresh review in Frontiers describes a mycelium-derived biochar platform โ essentially a carbon material from fungi that works as a prebiotic for soil microbes, a sensor, an energy storage device, and an environmental cleanup tool. One material โ a dozen applications. Mushrooms as the Swiss Army knife of environmental remediation.
Frontiers โ The Mushroom Matrix
Takeaway
Fungi might be the most underestimated organism on the planet. They’re not plants and not animals. They’re older than dinosaurs. They built the internet long before us (wood wide web). And now they’re becoming computers, building materials, antidepressants, and artists.
The fungal kingdom isn’t a niche. It’s a parallel technology platform we’re only beginning to understand. And judging by the pace of discoveries โ 2026 is shaping up to be the year of mushrooms.
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