Personal AI Operating Systems

Table of content

Ready-made systems that promise to be your AI-powered personal operating system. Some deliver, some don’t.

Quick Comparison

ProjectStarsFocusSetupActiveOpen SourceVerdict
AutoGPT181KAutonomous Agents3/5ActiveYesPioneer of autonomous agents
Open Interpreter62KCode Execution2/5Very ActiveYesBest for local code execution
CrewAI43KMulti-Agent Teams2/5Very ActiveYesBest for agent orchestration
Quivr39KRAG Second Brain3/5ActiveYesBest RAG framework
Khoj32KKnowledge + Search3/5Very ActiveYesBest all-rounder
Haystack24KRAG Pipelines3/5Very ActiveYesBest for production RAG
Letta21KPersistent Memory2/5Very ActiveYesBest for memory
Leon17KSelf-hosted Assistant3/5ActiveYesPrivacy-first
ClawdBot5.5KMulti-channel Chat3/5Very ActiveYesBest for messaging
PAI5.4KLife OS Blueprint3/5Very ActiveYesBest philosophy
AIOS5KAgent OS Research3/5ModerateYesAcademic focus
OpenDAN2KLocal AI OS3/5StalledYesNot recommended

Tier 1: Production Ready

AutoGPT

The original autonomous AI agent

AttributeValue
GitHubSignificant-Gravitas/AutoGPT
Stars181,337
LanguagePython
LicenseMIT
Last ActiveJan 2026

What it does:

Architecture:

LLM support: OpenAI GPT-4, GPT-3.5, local models via API

Setup:

git clone https://github.com/Significant-Gravitas/AutoGPT.git
cd AutoGPT && ./run setup
./run agent start

Verdict: The project that started the autonomous agent movement. Mature codebase, huge community. Best for learning agent concepts and experimentation.


Open Interpreter

Natural language interface to your computer

AttributeValue
GitHubopeninterpreter/open-interpreter
Stars61,758
LanguagePython
LicenseAGPL-3.0
Last ActiveJan 2026

What it does:

Key features:

LLM support: GPT-4, Claude, Llama, any OpenAI-compatible API

Setup:

pip install open-interpreter
interpreter
# Or with auto-approval (careful!)
interpreter -y

Verdict: The simplest way to give an LLM control of your local machine. Use in a sandbox for safety. Excellent developer experience.


CrewAI

Multi-agent orchestration framework

AttributeValue
GitHubcrewAIInc/crewAI
Stars42,990
LanguagePython
LicenseMIT
Last ActiveJan 2026

What it does:

Architecture:

Roles:

LLM support: Any LLM via LiteLLM (OpenAI, Anthropic, local models)

Setup:

pip install crewai crewai-tools
crewai create crew my-crew
cd my-crew && crewai run

Verdict: The leading multi-agent framework. Over 100K developers certified. Best when you need multiple specialized agents working together.


Quivr

Open-source RAG for your second brain

AttributeValue
GitHubQuivrHQ/quivr
Stars38,863
LanguagePython
LicenseApache 2.0
Last ActiveJan 2026

What it does:

File support: Text, Markdown, PDF, PowerPoint, Excel, CSV, Word, Audio, Video

LLM support: OpenAI, Anthropic, Mistral, Gemma, Ollama (local)

Vector stores: PGVector, Faiss, any compatible store

Setup:

# Cloud (instant)
# → quivr.com

# Self-hosted
git clone https://github.com/QuivrHQ/quivr.git
cd quivr && docker-compose up

Verdict: Best open-source RAG framework for document Q&A. Production-ready with cloud option. The “chat with your files” solution.


Khoj

AI second brain with knowledge management

AttributeValue
GitHubkhoj-ai/khoj
Stars32,229
LanguagePython
LicenseAGPL-3.0
Last ActiveJan 2026

What it does:

LLM support: Any model — GPT, Claude, Gemini, Llama, Qwen, Mistral, DeepSeek (local or cloud)

Integrations: Obsidian, Emacs, WhatsApp, Desktop, Browser

Setup:

# Cloud (instant, no setup)
# → app.khoj.dev

# Self-hosted
docker-compose up

Verdict: The most complete “second brain” solution. Works out of the box with cloud option. Self-hosting requires Docker knowledge.


Haystack

Production-grade RAG framework

AttributeValue
GitHubdeepset-ai/haystack
Stars23,942
LanguagePython
LicenseApache 2.0
Last ActiveJan 2026

What it does:

Pipeline capabilities:

LLM support: OpenAI, Anthropic, Cohere, local models

Notable users: Apple, Meta, Databricks, NVIDIA, PostHog

Setup:

pip install haystack-ai
# Create a simple RAG pipeline
from haystack import Pipeline
from haystack.components.retrievers import InMemoryBM25Retriever

Verdict: The enterprise choice for RAG. Used by major tech companies. Best when you need production-grade pipelines with monitoring and deployment.


Letta

Stateful agents with self-editing memory

AttributeValue
GitHubletta-ai/letta
Stars20,742
LanguagePython
LicenseApache 2.0
Last ActiveJan 2026

What it does:

Memory architecture:

LLM support: Model-agnostic (OpenAI, Anthropic, Ollama, vLLM)

Setup:

# Desktop app (easiest)
# → Download from letta.com

# CLI
npm install -g @letta-ai/letta-code
letta

# Docker
docker run letta/letta

Verdict: Best solution if you need agents that truly remember. The memory system is the most sophisticated available.


Leon

Privacy-first self-hosted assistant

AttributeValue
GitHubleon-ai/leon
Stars16,915
LanguageTypeScript
LicenseMIT
Last ActiveJan 2026

What it does:

Key features:

Setup:

npm install --global @leon-ai/cli
leon create birth
leon start

Verdict: The privacy purist’s choice. Everything runs on your server. Trade-off: fewer features than cloud-connected alternatives.


Tier 2: Specialized Use Cases

ClawdBot

Multi-channel AI assistant

AttributeValue
GitHubclawdbot/clawdbot
Stars5,468
LanguageTypeScript
LicenseMIT
Last ActiveJan 2026

What it does:

Best for: People who want AI assistance across all their messaging apps from one interface.

Setup:

npm install -g clawdbot@latest
clawdbot onboard --install-daemon

Verdict: The “Jarvis for your messages” solution. Impressive multi-channel support. Requires Node 22+.


PAI (Personal AI Infrastructure)

Goal-oriented life OS framework

AttributeValue
GitHubdanielmiessler/Personal_AI_Infrastructure
Stars5,385
LanguageTypeScript
LicenseMIT
Last ActiveJan 2026

What it does:

Key concept: Not just a chatbot — a system that knows your goals and helps pursue them.

Packs include:

Setup:

git clone https://github.com/danielmiessler/PAI.git
cd PAI/Releases/v2.3 && bun run install.ts

Requires: Claude Code (or similar agentic platform), Bun runtime

Verdict: Best philosophical framework for what a personal OS should be. Requires buy-in to Daniel Miessler’s vision and Claude Code.


AIOS

Operating system abstractions for AI agents

AttributeValue
GitHubagiresearch/AIOS
Stars4,960
LanguagePython
LicenseCustom
Last ActiveNov 2025

What it does:

Best for: Researchers and developers building multi-agent systems that need resource management.

Setup:

# Requires Python 3.10-3.11 specifically
git clone https://github.com/agiresearch/AIOS.git
pip install -r requirements.txt
git clone https://github.com/agiresearch/Cerebrum.git
pip install -e Cerebrum/

Verdict: Interesting academic project. More research-oriented than practical for personal use. Development has slowed.


OpenDAN

Personal AI OS (development stalled)

AttributeValue
GitHubfiatrete/OpenDAN-Personal-AI-OS
Stars1,988
LanguagePython
LicenseMIT
Last ActiveAug 2024

What it promised:

Why not recommended:

Verdict: Ambitious vision, but effectively abandoned. Look elsewhere.


Ratings Summary

Feature Matrix

FeatureAutoGPTOpen InterpreterCrewAIQuivrKhojHaystackLettaLeonClawdBotPAIAIOS
Persistent MemoryPluginNoSharedRAGPartialExternalBestNoPartialYesYes
Local/OfflineYesYesYesYesYesYesYesYesYesYesYes
Voice SupportNoYes (01)NoNoYesNoNoYesYesYesNo
Multi-LLMYesYesYesYesYesYesYesLimitedYesClaudeYes
Code ExecutionYesBestVia toolsNoNoNoVia toolsVia skillsNoYesYes
Document Q&ANoYesVia toolsBestBestBestYesNoVia skillsYesNo
Multi-AgentYesNoBestNoYesVia pipelinesNoNoNoYesYes
Web BrowsingYesYesYesNoYesYesVia toolsNoNoYesNo
API/SDKYesYesYesYesYesBestYesYesYesLimitedYes
Cloud OptionNoNoEnterpriseYesYesNoYesNoNoNoNo

Use Case Matrix

Use CaseBest ChoiceRunner-up
Autonomous task completionAutoGPTCrewAI
Local code executionOpen InterpreterAutoGPT
Multi-agent teamsCrewAIAutoGPT
Document Q&A / RAGQuivrKhoj
Knowledge managementKhojQuivr
Enterprise RAGHaystackQuivr
Persistent memoryLettaCrewAI
Full privacy/offlineLeonOpen Interpreter
Messaging integrationClawdBotNone comparable
Goal-oriented life OSPAINone comparable

Setup Complexity

ProjectRatingNotes
Open Interpreter2/5Single pip install
CrewAI2/5CLI scaffolding
Letta2/5Desktop app makes it easy
Khoj3/5Cloud option instant, Docker for self-host
AutoGPT3/5Script-based setup
Quivr3/5Docker compose, cloud option available
Haystack3/5Python package, requires pipeline building
Leon3/5CLI wizard helps
ClawdBot3/5Requires Node 22+
PAI3/5Requires Claude Code setup first
AIOS3/5Python 3.10-3.11 only
OpenDAN4/5Docker required, stability issues

Overall Recommendations

For autonomous agents: AutoGPT

For code execution: Open Interpreter

For multi-agent orchestration: CrewAI

For document Q&A: Quivr

For knowledge management: Khoj

For enterprise RAG: Haystack

For persistent memory: Letta

For privacy: Leon

For messaging integration: ClawdBot

For goal-oriented life OS: PAI

For research/multi-agent OS: AIOS


Build Your Own Instead?

These projects solve real problems, but they’re all opinionated. If your needs don’t match their design:

  1. Start with Claude Code or similar base
  2. Add memory with MCP servers
  3. Build skills for your specific workflows
  4. Iterate based on what you actually use

See Getting Started for the DIY approach.


Next: Claude Code Setup